Centre College Football Record (1950-1959)
| 1950 (6-1-1) |
| Centre | Opponent | | Location | Date |
| 26 | Tusculum College | 0 | Danville | September 30 |
| 14 | Maryville College | 7 | Maryville, TN | October 7 |
| 7 | Anderson University | 7 | Anderson, SC | October 14 |
| 9 | Wabash College | 7 | Danville | October 21 |
| 24 | Hanover College | 14 | Hanover, IN | October 28 |
| 24 | Rhodes College | 0 | Danville | November 4 |
| 16 | University of the South | 8 | Sewanee, TN | November 11 |
| 3 | Georgetown College | 7 | Danville | November 18 |
| |
| 1951 (5-1) |
| 14 | Maryville College | 6 | Maryville, TN | October 6 |
| 10 | University of Louisville (B-Team) | 7 | Danville | October 20 |
| 33 | Bethel College | 0 | McKenzie, TN | October 27 |
| 9 | University of Indianapolis | 6 | Indianapolis | November 4 |
| 0 | University of the South | 3 | Danville | November 10 |
| 21 | Georgetown College | 19 | Georgetown, KY | November 17 |
| |
| 1952 (4-3) |
| 20 | Maryville College | 0 | Danville | October 4 |
| 0 | Carson-Newman College | 33 | Danville | October 11 |
| 26 | Rhodes College | 6 | Memphis | October 18 |
| 49 | Bethel College | 6 | Danville | October 25 |
| 28 | University of Indianapolis | 31 | Indianapolis | November 1 |
| 14 | University of the South | 48 | Sewanee, TN | November 8 |
| 21 | Georgetown College | 13 | Danville | November 15 |
| Game with Maryville College was the first home night game for Centre |
| |
| 1953 (4-4) |
| 20 | Wilmington College | 6 | Danville | September 26 |
| 7 | Maryville College | 13 | Maryville, TN | October 3 |
| 0 | Carson-Newman College | 13 | Jefferson City, TN | October 10 |
| 32 | Rhodes College | 0 | Danville | October 17 |
| 33 | Franklin College | 6 | Danville | October 24 |
| 39 | Manchester College | 7 | Danville | October 31 |
| 14 | University of the South | 20 | Danville | November 7 |
| 13 | Defiance College | 19 | Danville | November 14 |
| |
| 1954 (5-3) |
| 9 | Wilmington College | 0 | Wilmington, OH | September 25 |
| 7 | Maryville College | 12 | Danville | October 2 |
| 20 | Carson-Newman College | 40 | Danville | October 9 |
| 14 | Rhodes College | 0 | Memphis | October 16 |
| 6 | University of Louisville | 27 | Louisville | October 23 |
| 21 | Hanover College | 6 | Danville | October 30 |
| 21 | University of the South | 7 | Sewanee, TN | November 6 |
| 61 | Washington & Jefferson College | 14 | Danville | November 13 |
| |
| 1955 (8-0) |
| 28 | Otterbein College | 13 | Danville | September 17 |
| 17 | Maryville College | 0 | Maryville, TN | October 1 |
| 24 | Washington & Lee University | 7 | Lexington, VA | October 8 |
| 28 | Rhodes College | 13 | Danville | October 15 |
| 53 | Georgetown College | 0 | Danville | October 22 |
| 27 | Hanover College | 13 | Hanover, IN | October 29 |
| 28 | University of the South | 0 | Danville | November 5 |
| 40 | Washington & Jefferson College | 7 | Washington, PA | November 12 |
| Centre turned down the 1955 Tangerine Bowl bid |
| |
| 1956 (6-2) |
| 13 | Wilmington College | 0 | Wilmington, OH | September 22 |
| 20 | Maryville College | 13 | Danville | September 20 |
| 14 | Washington & Lee University | 6 | Danville | October 6 |
| 27 | Rhodes College | 13 | Memphis | October 13 |
| 26 | Georgetown College | 7 | Georgetown, KY | October 19 |
| 13 | Hanover College | 27 | Danville | October 27 |
| 0 | University of the South | 26 | Sewanee, TN | November 3 |
| 26 | Bluffton University | 12 | Danville | November 10 |
| |
| 1957 (4-4) |
| 9 | Wilmington College | 0 | Wilmington, OH | September 21 |
| 7 | Maryville College | 19 | Maryville, TN | September 28 |
| 7 | Washington & Lee University | 6 | Lexington, VA | October 5 |
| 21 | Rhodes College | 13 | Danville | October 12 |
| 7 | Georgetown College | 12 | Danville | October 19 |
| 19 | Hanover College | 26 | Hanover, IN | October 26 |
| 7 | University of the South | 0 | Danville | November 2 |
| 19 | Bluffton University | 26 | Bluffton, OH | November 9 |
| |
| 1958 (5-3) |
| 7 | Wilmington College | 6 | Wilmington, OH | September 20 |
| 12 | Maryville College | 7 | Danville | September 27 |
| 27 | Washington & Lee University | 8 | Danville | October 4 |
| 7 | Rhodes College | 6 | Memphis | October 11 |
| 0 | Georgetown College | 13 | Georgetown, KY | October 18 |
| 20 | Hanover College | 13 | Danville | October 25 |
| 0 | University of the South | 20 | Sewanee, TN | November 1 |
| 16 | Bluffton University | 19 | Danville | November 8 |
| |
| 1959 (3-3-2) |
| 20 | Wilmington College | 7 | Danville | September 19 |
| 8 | Washington & Lee University | 45 | Lexington, VA | September 26 |
| 23 | Maryville College | 6 | Maryville, TN | October 3 |
| 26 | Rhodes College | 21 | Danville | October 10 |
| 14 | Hanover College | 14 | Hanover, IN | October 24 |
| 0 | University of the South | 0 | Danville | October 31 |
| 14 | Hampden-Sydney College | 18 | Hampden-Sydney, VA | November 14 |
| 21 | Emory & Henry College | 22 | Danville | November 28 |
| |
